背景描述 |
Hepatocyte Growth Factor (HGF) activates c-Met receptor's tyrosine kinase cascade, influencing cell growth and motility. Originating from mesenchymal cells, HGF is a multifunctional cytokine that plays a central role in angiogenesis, tumorigenesis, and tissue regeneration. Initially secreted as an inactive polypeptide, HGF undergoes cleavage to become an active heterodimeric molecule. The gene exhibits alternative splicing, resulting in diverse isoforms. |
别称 |
Hepatocyte growth factor, Hepatopoietin-A,
Scatter factor (SF), HPTA |
蛋白编码 |
P14210 |
分子量 |
The protein has a calculated MW of 80.48 kDa.
The protein migrates as 75-100 kDa under reducing condition (SDS-PAGE analysis). |
表达系统 |
HEK293 cell |
纯度 |
>90% as determined by SDS-PAGE analysis. |
生物活性 |
Testing in process |
内毒素检测 |
<1 EU per 1 μg of the protein by the LAL method. |
蛋白序列 |
A DNA sequence encoding Human HGF Protein (#P14210)(Gln 32-Ser 728) was expressed with polyhistidine tag at the C-terminus. |
蛋白标签 |
His Tag (C-term) |
产品形式 |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
产品应用 |
Cell Culture |