cytokine

重组人细胞程序性死亡-配体1 /Recombinant PD-L1， Human， HEK293，Animal-Free

说明书下载

产品编号	优惠促销	规格	价格	货期
CM191-5HP	买一赠一	5 ug	￥600.00	现货
CM191-20HP	买一赠一	20 ug	￥1500.00	现货
CM191-100HP		100 ug	￥4500.00	现货
CM191-500HP		500 ug	￥13000.00	请询
CM191-1000HP		1 mg	￥20000.00	请询

在线咨询

产品简介

背景描述	PD-L1 regulates immune responses by binding to the immunoinhibitory receptor PD-1 on activated T-cells and B-cells. This interaction can suppress T-cell responses by inducing apoptosis and arresting cell-cycle progression. In cancer, PD-L1's role in reducing antigen-specific T cells can promote tumor growth and immune evasion. As a result, PD-L1 is considered as a potential therapeutic target for autoimmune diseases and cancer.
别称	CD274, B7-H1
蛋白编码	Q9NZQ7.1
分子量	The protein has a calculated MW of 26 kDa. The protein migrates as 30-35 kDa uder reducing condition (SDS-PAGE analysis).
表达系统	HEK293 cell
纯度	>95% as determined by SDS-PAGE analysis.
生物活性	Measure by its ability to induce adhesion in T-cell enriched PBMC cultures using a concentration range of 1-2 μg/mL.
内毒素检测	<0.1 EU per 1 μg of the protein by the LAL method.
蛋白序列	A DNA sequence encoding Human PD-L1 Protein (#Q9NZQ7.1)(Phe19-Arg238) was expressed with polyhistidine tag at the C-terminus.
蛋白标签	His Tag (C-term)
产品形式	The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
产品应用	Cell Culture

产品储存/运输

储存	Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.
运输	Blue Ice

产品使用

Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

实验数据展示

SDS- PAGE analysis of recombinant human PD-L1

文献引用

暂无参考文献