背景描述 |
OX40L is a 16.86 kDa tumor necrosis factor family protein with 150 amino acid residues. OX40L is mainly expressed from lymphoid tissue, and promotes T-cell proliferation, survival, activation and cytokine production through receptor binding on the surface of T cells (OX40). |
别称 |
TNFSF4,Ath, Ath-, Ath-1, Ath1, CD134, CD134L, OX-40L, OX4, TXGP1, Tnlg2b, Txgp, Txgp1l, gp3, gp34 |
蛋白编码 |
P43488 |
分子量 |
The protein has a calculated MW of 17.68 kDa.
The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis). |
表达系统 |
Escherichia coli |
纯度 |
>95% as determined by SDS-PAGE. |
生物活性 |
Measure by its ability to induce IL-2 secretion in mouse T cells in the presence of the anti-CD3 antibody.
The ED₅₀ for this effect is <25 ng/mL. |
内毒素检测 |
<0.1 EU per 1 μg of the protein by the LAL method. |
蛋白序列 |
QLSSSPAKDPPIQRLRGAVTRCEDGQLFISSYKNEYQTMEVQNNSVVIKCDGLYIIYLKGSFFQEVKIDLHFREDHNPISIPMLNDGRRIVFTVVASLAFKDKVYLTVNAPDTLCEHLQINDGELIVVQLTPGYCAPEGSYHSTVNQVPL with polyhistidine tag at the N-terminus. |
蛋白标签 |
His Tag (N-term) |
产品形式 |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
产品应用 |
Cell Culture |