Human ACE2 (Angiotensin-Converting Enzyme 2), Fc tag, HEK293
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Product Specifications
Background Angiotensin-Converting Enzyme 2 (ACE2) has a function as an enzyme that hydrolysis the angiotensin II into angiotensin which do the effect of anti-oxidation and anti-inflammatory in cardiovascular system through the inhibition of MAPK pathway and TGF β signaling pathway. ACE2 is highly expression in intestines, kidney, and heart. It is also fonud highy expression in patients with lung cancer.
Synonyms Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, ACEH, Angiotensin-converting enzyme-related carboxypeptidase, ACE-related carboxypeptidase, Metalloprotease MPROT15
Uniprot ID Q9BYF1
Molecular Weight The protein has a calculated MW of 109.67 kDa.The protein migrates as 120-170 kDa under reducing condition (SDS-PAGE analysis).
Expression System HEK293 cell
Purity >98% as determined by SDS-PAGE analysis.
Protein Sequence Gln18-Ser740
Protein Tag Fc Tag (C-terminal)
Form Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Storage/Shipping
Stability & Storage Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.
Shipping Blue Ice
Product Note
Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at RT for at least 20 min to ensure sufficient re-dissolved.
Scientific Data
No experimental data is available
Citations
No references are available
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