SARS-CoV-2 Trimeric Spike Protein (Beta B1.351 Variant), His Tag, HEK293

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Product Specifications

Background	Coronaviruses (Beta B1.351 Variant) are enveloped positive-sense RNA viruses. Spike protein on the viral envelope and the cognate receptor on the surface of host cells that are essential for entry into host cells upon receptor binding and membrane fusion. Spike proteins are target for neutralization antibody, and mediate membrane fusion and virus entry.Trimeric spike protein is about 180 kDa, and contains two subunits, S1 and S2, mediating attachment and membrane fusion.
Synonyms	Spike glycoprotein, S glycoprotein, E2, Peplomer protein
Uniprot ID	QUT645
Molecular Weight	The protein has a calculated MW of 133.67 kDa. The protein migrates above 180 kDa under reducing condition (SDS-PAGE analysis). The protein migrates as 75-100 kDa under reducing condition (SDS-PAGE analysis).
Expression System	HEK293 cell
Purity	>95% as determined by SDS-PAGE analysis.
Protein Sequence	Ser13-Pro1210
Protein Tag	His Tag (C-term)
Form	Liquid. Phosphate buffered saline, pH 7.4.

Product Note

Centrifuge at 3000 rpm for 5 mins before opening. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Storage/Shipping

Stability & Storage	Store at 2°C to 8°C for up to 2 weeks, -80°C for 6 months. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -80°C for 6 months. Avoid repeated freeze/thaw cycles.
Shipping	Blue Ice

Scientific Data

No experimental data is available

Citations

No references are available