| Background |
PROS1, also known as protein S, is a vitamin K-dependent protein that plays a crucial role in the regulation of blood coagulation. It functions as a cofactor for protein C, another key player in the coagulation cascade.
PROS1 acts as an anticoagulant by inhibiting the activity of certain clotting factors and promoting the breakdown of blood clots. It helps maintain the balance between clotting and anticoagulation, preventing the formation of excessive blood clots that can lead to thrombosis. |
| Synonyms |
PROS, Vitamin K-dependent protein S |
| Uniprot ID |
P07225 |
| Molecular Weight |
The protein has a calculated MW of 82.89 kDa.
The protein migrates as 75 kDa uder reducing condition (SDS-PAGE analysis). |
| Expression System |
Escherichia coli |
| Purity |
>95% as determined by SDS-PAGE analysis. |
| Activity |
Testing in process |
| Endotoxin Level |
<1 EU per 1 μg of the protein by the LAL method. |
| Protein Sequence |
A DNA sequence encoding Human PROS1 Protein (#P07225)(Ala42-Ser676) was expressed with polyhistidine-SUMO tag at the N-terminus. |
| Protein Tag |
His-SUMO Tag (N-term) |
| Form |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
| Application |
Cell Culture |
No references are available
