| Background |
Fibroblast Growth Factors-16 (FGF-16) is a 23.8 kDa member of the fibroblast Growth Factors with 207 amino acid residues. FGF-16 is mainly expressed from melanocytes, fibroblasts. FGF-16 involved embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. |
| Synonyms |
fibroblast growth factor 16, FGFG, FGF16 |
| Uniprot ID |
O43320 |
| Molecular Weight |
The protein has a calculated MW of 24.57 kDa.
The protein migrates as 24 kDa under reducing condition (SDS-PAGE analysis). |
| Expression System |
Escherichia coli |
| Purity |
>95% as determined by SDS-PAGE. |
| Activity |
Measure by its ability to induce 3T3 cells proliferation.
The ED₅₀ for this effect is <31 ng/mL.
The specific activity of recombinant human FGF-16 is > 3 x 10⁴ IU/mg. |
| Endotoxin Level |
<0.1 EU per 1 μg of the protein by the LAL method. |
| Protein Sequence |
MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPV DPSKLPSMSR DLFHYR with polyhistidine tag at the C-terminus. |
| Protein Tag |
His Tag (C-term) |
| Form |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
| Application |
Cell Culture |
No references are available
