背景描述 |
Galectin-7 (Gal-7) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-7 is constitutively presented in the gastrointestinal tract, stratified epithelia, skin, and fetal heart. It has been reported that galectin-7 serves as an effector in triggering apoptosis following activation of the p53 pathway. Furthermore, it serves important functions in numerous biological activities including cell adhesion, migration, proliferation, and differentiation. |
别称 |
LGALS7B, LGALS7, PI7; GAL7, Gal-7, HKL-14 |
蛋白编码 |
P47929 |
分子量 |
The protein has a calculated MW of 15.9 kDa.
The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis). |
表达系统 |
Escherichia coli |
纯度 |
>98% as determined by SDS-PAGE. |
生物活性 |
Measure by its ability to chemoattract human THP1 cells. Chemotactic activity was observed at a concentration of 0.5 μg/mL. |
内毒素检测 |
<0.1 EU per 1 μg of the protein by the LAL method. |
蛋白序列 |
SNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF with polyhistidine tag at the N-terminus. |
蛋白标签 |
His Tag (N-term) |
产品形式 |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
产品应用 |
Cell Culture |