背景描述 |
Galectin-2 (Gal-2) is a lectin family member and structurally closely related to galectin-1. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-2 serves as a proapoptotic effector for activated T cells through caspase-3 signaling. Moreover, galectin-2 has emerged as a crucial factor in driving the macrophage to CD40-positive M1 polarization, leading to arteriogenesis attenuation and collateral arteries remodeling. |
别称 |
LGALS2, HL14 |
蛋白编码 |
P05162 |
分子量 |
The protein has a calculated MW of 15.5 kDa.
The protein migrates as 15 kDa under reducing condition (SDS-PAGE analysis). |
表达系统 |
Escherichia coli |
纯度 |
>98% as determined by SDS-PAGE. |
生物活性 |
Measure by its ability to chemoattract human THP1 cells using a concentration range of 2.5-25 µg/mL. |
内毒素检测 |
<0.1 EU per 1 μg of the protein by the LAL method. |
蛋白序列 |
TGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE with polyhistidine tag at the N-terminus. |
蛋白标签 |
His Tag (N-term) |
产品形式 |
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us. |
产品应用 |
Cell Culture |